Cystinuria is a disease involving a defect in the movement of certain amino acids, the building blocks of proteins, into and out of cells, particularly in the kidney. Normally in the kidney, amino acids and some other substances are filtered out of the blood, and then reclaimed from the urine. In Cystinuria, some amino acids are not reabsorbed by the kidney, and can reach high concentrations in the urine.
One of the amino acids involved, Cystine, has a tendency to precipitate in acidic urine and lead to the formation of kidney and bladder stones that can cause severe illness as they irritate the urinary track system and sometimes cause blockage.
Testing a dog for Cystinuria is accomplished by the collection and submission of a urine sample to a laboratory for testing.
There are also genetic tests available for this disease.
Diet is also thought to have an effect on the amount of amino acids in the body and it is also recommended that a Dogs diet does not contain large amounts of chicken.
Testing should be performed on BOTH sire and dam prior to breeding.